More than £6,000 worth of illegal drugs were seized during raids across houses in the Rotherham, Barnsley and Doncaster areas.
The three-day operation started last Wednesday morning when officers executed warrants at six properties in Thurnscoe and
elsewhere in the Barnsley area.
They found nearly £3,000 worth of heroin, cannabis and amphetamines while three people were arrested and others were given cautions.
On Thursday more than £2,500 worth of cannabis and what was suspected to be heroin were recovered during several raids in Swinton, West Melton and Wath. Six people were arrested and questioned.
On the final day police raided five suspected drugs dens in Mexborough where they recovered £980 worth of heroin, cannabis, diazepam and methadone. Six people were arrested.
The operation, which pulled in resources from all three police districts, also targeted other crimes.
A further 29 people were arrested for a range of crimes from burglary and assault to non payment of fines and failing to attend court.
Police recovered more than £11,000 cash and over £29,000 worth of property. They also seized 11 vehicles, some of which were suspected to be stolen and some were for documentation offences.
The operation was delivered by the area's Safer Neighbourhood Teams and was led by Doncaster's Tasking Team.
Additional specialist police officers and external agencies including the Driver Vehicle Licensing Agency (DVLA), HM Customs and Vehicle Operator Services Agency (VOSA) were also involved.
This was the second phase of Operation Dynamite which started last November and saw similar results.
It is the first time that officers from Safer Neighbourhood Areas in three districts, Barnsley, Rotherham and Doncaster have teamed up to tackle crime in this way, but police warned it wouldn't be the last.
Superintendent Ged Gamble, of Doncaster Police, said: "Criminals don't respect police borders, so I felt it was time to join forces with neighbouring districts again, to get ahead of the game.
"We've achieved this by sharing information and pooling resources to such good effect that we've been able to target offenders and positively disrupt their activity.
"Criminals now know that whether they offend in Doncaster, Rotherham or Barnsley, we will catch up with them."
